Prof. Dr. Markus Neuhäuser
Prodekan
- Maximum test and adaptive test for the general two-sample problem
Murakami, Hidetoshi; Kitani, Masato; Neuhäuser, Markus - Coronary Artery Bypass Graft Surgery in Patients With Acute Coronary Syndromes After Primary Percutaneous Coronary Intervention: A Current Report From the North‐Rhine Westphalia Surgical Myocardial Infarction Registry
Thielmann, Matthias; Wendt, Daniel; Slottosch, Ingo et al. - Predictors of pre-European deforestation on Pacific islands : A re-analysis using modern multivariate non-parametric statistical methods
Schenk, Alina; Neuhäuser, Markus; Ruxton, Graeme D. et al. - Turn alternation and the influence of environmental factors on search routes through branched structures by ladybirds (Coccinella septempunctata and Adalia bipunctata)
Humphreys, Rosalind K.; Neuhäuser, Markus; Ruxton, Graeme D. - Unequal sample sizes according to the square‐root allocation rule are useful when comparing several treatments with a control
Neuhäuser, Markus; Mackowiak, Malwina M.; Ruxton, Graeme D. - Intraoperative Hemoadsorption in Patients With Native Mitral Valve Infective Endocarditis
Haidari, Zaki; Wendt, Daniel; Thielmann, Matthias et al. - Substantially inflated type I error rates if propensity score method is not fixed in advance
Neuhäuser, Markus; Kraechter, Julia M.; Thielmann, Matthias et al. - Surgical revascularization for acute coronary syndromes : a report from the North Rhine-Westphalia surgical myocardial infarction registry
Liakopoulos, Oliver J; Slottosch, Ingo; Wendt, Daniel et al. - Early Clinical Outcomes of Surgical Myocardial Revascularization for Acute Coronary Syndromes Complicated by Cardiogenic Shock : A Report From the North‐Rhine‐Westphalia Surgical Myocardial Infarction Registry
Liakopoulos, Oliver J.; Schlachtenberger, G.; Wendt, Daniel et al. - Striving for Simple but Effective Advice for Comparing the Central Tendency of Two Populations
Ruxton, Graeme; Neuhäuser, Markus - A non-parametric maximum test for the Behrens–Fisher problem
Welz, Anke; Ruxton, Graeme D.; Neuhäuser, Markus - Liver transplantation for hepatocellular carcinoma with live donors or extended criteria donors : a propensity score-matched comparison
Sotiropoulos, Georgios C.; Spartalis, Eleftherios; Machairas, Nikolaos et al. - Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
Bøtker, Hans Erik; Hausenloy, Derek; Andreadou, Ioanna et al. - Some comments on the update to BJP guidance on experimental design and analysis
Neuhäuser, Markus; Ruxton, Graeme D - Underestimation of Pearson’s product moment correlation statistic
Humphreys, Rosalind K.; Puth, Marie-Therese; Neuhäuser, Markus et al. - Das Geheimnis des Storchenflugs
Eder, Heinrich; Fiedler, Wolfgang; Neuhäuser, Markus - No protection of heart, kidneys and brain by remote ischemic preconditioning before transfemoral transcatheter aortic valve implantation : Interim-analysis of a randomized single-blinded, placebo-controlled, single-center trial
Kahlert, Philipp; Hildebrandt, Heike Annelie; Patsalis, Polykarpos Christos et al. - Quantification and characterisation of released plaque material during bioresorbable vascular scaffold implantation into right coronary artery lesions by multimodality intracoronary imaging
Hildebrandt, Heike; Patsalis, Polykarpos; Al-Rashid, Fadi et al. - The number of strata in propensity score stratification for a binary outcome
Neuhäuser, Markus; Thielmann, Matthias; Ruxton, Graeme D. - Advice on testing the null hypothesis that a sample is drawn from a normal distribution
Ruxton, Graeme D.; Wilkinson, David M.; Neuhäuser, Markus - Combining the t test and Wilcoxon's rank-sum test
Neuhäuser, Markus - Confounders of Cardioprotection by Remote Ischemic Preconditioning in Patients Undergoing Coronary Artery Bypass Grafting
Kleinbongard, Petra; Neuhäuser, Markus; Thielmann, Matthias et al. - Conventional aortic valve replacement or transcatheter aortic valve implantation in patients with previous cardiac surgery
Wendt, Daniel; Al-Rashid, Fadi; Kahlert, Philipp et al. - Data from : On the variety of methods for calculating confidence intervals by bootstrapping
Puth, Marie-Therese; Neuhäuser, Markus; Ruxton, Graeme D. - Effective use of Spearman's and Kendall's correlation coefficients for association between two measured traits
Puth, Marie-Therese; Neuhäuser, Markus; Ruxton, Graeme D. - Evaluation of aerodynamic parameters from infrared laser tracking of free-gliding white storks
Eder, Heinrich; Fiedler, Wolfgang; Neuhäuser, Markus - Heart rate reduction and longevity in mice
Gent, Sabine; Kleinbongard, Petra; Dammann, Philip et al. - Intraaortic Protection From Embolization in Patients Undergoing Transaortic Transcatheter Aortic Valve Implantation
Wendt, Daniel; Kleinbongard, Petra; Knipp, Stephan et al. - On the variety of methods for calculating confidence intervals by bootstrapping
Puth, Marie-Therese; Neuhäuser, Markus; Ruxton, Graeme D. - Rotating plates: Online study demonstrates the importance of orientation in the plating of food
Michel, Charles; Woods, Andy T.; Neuhäuser, Markus et al. - Statistical tests for the comparison of two samples : The general alternative
Neuhäuser, Markus; Welz, Anke; Ruxton, Graeme D. - Was beeinflusst die Schnabellänge des Eisvogels Alcedo atthis?
Neuhäuser, Markus; Bunzel-Drüke, M.; Zimball, O. - Effective use of Pearson's product-moment correlation coefficient
Puth, Marie-Therese; Neuhäuser, Markus; Ruxton, Graeme D. - Hinweise zur Studienplanung, Biometrie und klinischen Epidemiologie
Scherag, A.; Hirche, H.; Ose, C. et al. - The new St Jude Trifecta versus Carpentier-Edwards Perimount Magna and Magna Ease aortic bioprosthesis : is there a hemodynamic superiority?
Wendt, Daniel; Thielmann, Matthias; Plicht, Björn et al. - A modified combination test for the analysis of a clinical trial when a protocol amendment changed the inclusion criteria
Leuchs, Ann-Kristin; Neuhäuser, Markus - Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trial
Thielmann, Matthias; Kottenberg, Eva; Kleinbongard, Petra et al. - Circular statistics in R
Pewsey, Arthur; Neuhäuser, Markus; Ruxton, Graeme D. - Estimation of the treatment effect in the presence of non-compliance and missing data
Leuchs, Ann-Kristin; Zinserling, Jörg; Schlosser-Weber, Gabriele et al. - Gründe für von der Fraktionsdisziplin abweichendes Abstimmungsverhalten bei Bundestagsabgeordneten
Neuhäuser, Alice; Mischler, Maike; Ruxton, Graeme D. et al. - Improving the reporting of p-values generated by randomization methods
Ruxton, Graeme D.; Neuhäuser, Markus - Management of high-risk patients with aortic stenosis and coronary artery disease
Wendt, Daniel; Kahlert, Philipp; Lenze, Tim et al. - Review of alternative approaches to calculation of a confidence interval for the odds ratio of a 2x2 contingency table
Ruxton, Graeme D.; Neuhäuser, Markus - Biostatistik
Neuhäuser, Markus - Nonparametric statistical tests : a computational approach
Neuhäuser, Markus - Prognostic significance of cardiac troponin I on admission for surgical treatment of acute pulmonary embolism: a single-centre experience over more than 10 years
Thielmann, Matthias; Pasa, Susanne; Wendt, Daniel et al. - A new location-scale test based on a combination of the ideas of Levene and Lepage
Neuhäuser, Markus; Leuchs, Ann-Kristin; Ball, Dorothee - Permutation tests
Neuhäuser, Markus - Transformations can be avoided when comparing skewed distributions with unequal variances
Neuhäuser, Markus - Wilcoxon-Mann-Whitney test
Neuhäuser, Markus - Wilcoxon-Signed-Rank Test
Rey, Denise; Neuhäuser, Markus - A nonparametric two-sample comparison for skewed data with unequal variances
Neuhäuser, Markus - A SAS/IML algorithm for exact nonparametric paired tests
Neuhäuser, Markus; Leuchs, Ann-Kristin - An equivalence test based on n and p
Neuhäuser, Markus - Comparing samples with large numbers of zeros
Ruxton, Graeme D.; Rey, Denise; Neuhäuser, Markus - Computer-intensive und nichtparametrische statistische Tests
Neuhäuser, Markus - Good practice in testing for an association in contingency tables
Ruxton, Graeme D.; Neuhäuser, Markus - Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrest
Thielmann, Matthias; Kottenberg, Eva; Boengler, Kerstin et al. - Risk prediction and outcomes in patients with liver cirrhosis undergoing open-heart surgery
Thielmann, Matthias; Mechmet, Achmet; Neuhäuser, Markus et al. - The comparison of mean crowding between two groups
Neuhäuser, Markus; Kotzmann, Jana; Walier, Maja et al. - When should we use one-tailed hypothesis testing?
Ruxton, Graeme D.; Neuhäuser, Markus - A Maximum Test for the Analysis of Ordered Categorical Data
Neuhäuser, Markus - A SAS/IML algorithm for an exact permutation test
Neuhäuser, Markus; Schulz, Andreas; Czech, Daniel - Extra-pair young in house wren broods are more likely to be male than female
Johnson, L. Scott; Thompson, Charles F.; Sakaluk, Scott K. et al. - Hinweise zur Studienplanung, Biometrie und klinischen Epidemiologie
Jöckel, K.-H.; Hirche, H.; Neuhäuser, Markus - Impact of prior percutaneous coronary intervention on the outcome of coronary artery bypass surgery: A multicenter analysis
Massoudy, Parwis; Thielmann, Matthias; Lehmann, Nils et al. - Nonparametric trend tests for right-censored survival times
Leissen, Sandra; Ligges, Uwe; Neuhäuser, Markus et al. - Predicting pressure ulcer risk: a multifactorial approach to assess risk factors in a large university hospital population
Nonnemacher, Michael; Stausberg, Jürgen; Bartoszek, Gabriele et al. - Results of a propensity score-matched comparison of the Perimount Magna and Mosaic Ultra aortic valve prostheses
Wendt, Daniel; Buck, Thomas; Jánosi, Rolf A. et al. - Round your numbers in rank tests : exact and asymptotic inference and ties
Neuhäuser, Markus; Ruxton, Graeme D. - The analysis of multicentre clinical trials when there is heterogeneity between centres
Neuhäuser, Markus; Senske, Roswitha - The importance of the biological system underlying the data when choosing a statistical test : why penguins need to be treated differently to parasites
Neuhäuser, Markus - A note on the use of the non-parametric Wilcoxon-Mann-Whitney test in the analysis of medical studies
Neuhäuser, Markus; Kühnast, C. - Comparison between Minimally Invasive Video-Assisted Thyroidectomy and Conventional Thyroidectomy : Is There Any Evidence-Based Information?
Sgourakis, George; Sotiropoulos, Georgios C.; Neuhäuser, Markus et al. - Distribution-free two-sample comparisons in the case of heterogeneous variances
Neuhäuser, Markus; Ruxton, Graeme D. - Immobility of patients in medical and orthopaedic departments : a German-wide survey
Kröger, Knut; Weiland, Dorothea; Wagener, Thomas et al. - Insights from complete-incomplete brood sex-ratio disparity
Krackow, Sven; Neuhäuser, Markus - New resampling method for evaluating stability of clusters
Gana Dresen, Irina; Boes, Tanja; Hüsing, Johannes et al. - R0 Liver Resections for Primary Malignant Liver Tumors in the Noncirrhotic Liver: A Diagnosis-Related Analysis
Sotiropoulos, Georgios C.; Bockhorn, Maximilian; Sgourakis, George et al. - The statistical analysis of a clinical trial when a protocol amendment changed the inclusion criteria
Lösch, Christian; Neuhäuser, Markus - A comparative study of nonparametric two-sample tests after Levene's transformation
Neuhäuser, Markus - Adaptive management of data quality in cohort studies and registers : proposal for a guideline
Nonnemacher, Michael; Weiland, Dorothea; Neuhäuser, Markus et al. - Adaptive-filtering of trisomy 21 : risk of Down syndrome depends on family size and age of previous child
Neuhäuser, Markus; Krackow, Sven - Climate change and the arrival of self-introduced bird species in New Zealand
Neuhäuser, Markus; Cuming, P. - Hilar lymph nodes sampling at the time of liver transplantation for hepatocellular carcinoma: to do or not to do?
Sotiropoulos, Georgios C.; Malagó, Massimo; Molmenti, Ernesto P. et al. - Lipid-lowering effect of preoperative statin therapy on postoperative major adverse cardiac events after coronary artery bypass surgery
Thielmann, Matthias; Neuhäuser, Markus; Marr, Anja et al. - Liver Transplantation for Hepatocellular Carcinoma: University Hospital Essen Experience and Metaanalysis of Prognostic Factors
Sotiropoulos, Georgios C.; Lang, Hauke; Nadalin, Silvio et al. - Predictors and Outcomes of Coronary Artery Bypass Grafting in ST Elevation Myocardial Infarction
Thielmann, Matthias; Neuhäuser, Markus; Marr, Anja et al. - Prognostic impact of previous percutaneous coronary intervention in patients with diabetes mellitus and triple-vessel disease undergoing coronary artery bypass surgery
Thielmann, Matthias; Neuhäuser, Markus; Knipp, Stephan et al. - Pseudo-precision in Gene Expression Values Can Reduce Efficiency
Neuhäuser, Markus; Boes, T.; Jöckel, K.-H. - Reliability and validity of ICARS in focal cerebellar lesions
Schoch, Beate; Regel, Jens Peter; Frings, Markus et al. - The Chen–Luo test in case of heteroscedasticity
Neuhäuser, Markus; Lösch, Christian; Jöckel, Karl-Heinz - A Bootstrap Test for the Analysis of Microarray Experiments with a Very Small Number of Replications
Neuhäuser, Markus; Jöckel, Karl-Heinz - A robust modification of the ordered-heterogeneity test
Neuhäuser, Markus; Hothorn, Ludwig A. - Administration of C1-esterase inhibitor during emergency coronary artery bypass surgery in acute ST-elevation myocardial infarction
Thielmann, M.; Marggraf, G.; Neuhäuser, M. et al. - An attempt at data verification in the EACTS Congenital Database : data before and after verification differ significantly
Neuhäuser, Markus; Lehmann, Nils; Nonnemacher, Michael et al. - An exact test for trend among binomial proportions based on a modified Baumgartner-Weiß-Schindler statistic
Neuhäuser, Markus - Assessing the prevalence of the Metabolic Syndrome according to NCEP ATP III in Germany : feasibility and quality aspects of a two step approach in 1550 randomly selected primary health care practices.
Moebus, Susanne; Hanisch, Jens Ulrich; Neuhäuser, Markus et al. - Does perioperative administration of rofecoxib improve analgesia after spine, breast and orthopaedic surgery?
Riest, G.; Peters, J.; Weiss, M. et al. - Emergency re-revascularization with percutaneous coronary intervention, reoperation, or conservative treatment in patients with acute perioperative graft failure following coronary artery bypass surgery
Thielmann, M.; Massoudy, P.; Jäger, B. et al. - How to deal with multiple endpoints in clinical trials
Neuhäuser, Markus - Liver Transplantation and Incidentally Found Hepatocellular Carcinoma in Liver Explants : Need for a New Definition?
Sotiropoulos, Georgios C.; Malagó, Massimo; Molmenti, Ernesto P. et al. - Management of data quality : development of a computer-mediated guideline
Stausberg, J.; Nonnemacher, M.; Weiland, D. et al. - Maximum Tests are Adaptive Permutation Tests
Neuhäuser, Markus; Hothorn, Ludwig A. - Methacholine challenge tests : sample sizes required in crossover trials
Neuhäuser, Markus; Jöckel, K.-H. - Muscle force and fatigue in patients with sepsis and multiorgan failure
Eikermann, M.; Koch, G.; Gerwig, M. et al. - No association of the NFKB1 insertion/deletion promoter polymorphism with survival in colorectal and renal cell carcinoma as well as disease progression in B-cell chronic lymphocytic leukemia
Riemann, Kathrin; Becker, Lucie; Struwe, Henrike et al. - Over-expression of p53/BAK in aseptic loosening after total hip replacement
Landgraeber, Stefan; Toetsch, Martin; Wedemeyer, Christian et al. - Postoperative Upper Airway Obstruction After Recovery of the Train of Four Ratio of the Adductor Pollicis Muscle from Neuromuscular Blockade
Eikermann, Matthias; Blobner, Manfred; Groeben, Harald et al. - Prognostic Significance of Multiple Previous Percutaneous Coronary Interventions in Patients Undergoing Elective Coronary Artery Bypass Surgery
Thielmann, M.; Leyh, R.; Massoudy, P. et al. - Prognostic Value of Preoperative Cardiac Troponin I in Patients Undergoing Emergency Coronary Artery Bypass Surgery With Non-ST-Elevation or ST-Elevation Acute Coronary Syndromes
Thielmann, M.; Massoudy, P.; Neuhäuser, M. et al. - Surgery for Hepatocellular Carcinoma Arising in Hereditary Hemochromatosis
Sotiropoulos, Georgios C.; Molmenti, Ernesto P.; Lang, Hauke et al. - Thyrotropin Receptor Autoantibodies Are Independent Risk Factors for Graves’ Ophthalmopathy and Help to Predict Severity and Outcome of the Disease
Eckstein, Anja K.; Plicht, Marco; Lax, Hildegard et al. - β-Ray brachytherapy with 106Ru plaques for retinoblastoma
Schüler, Andreas O.; Flühs, Dirk; Anastassiou, Gerassimos et al. - Adaptive designs based on the truncated product method
Neuhäuser, Markus; Bretz, Frank - Age at diagnosis of isolated unilateral retinoblastoma does not distinguish patients with and without a constitutional RB1 gene mutation but is influenced by a parent-of-origin effect
Schüler, A.; Weber, S.; Neuhäuser, M. et al. - Diagnostic discrimination between graft-related and non-graft-related perioperative myocardial infarction with cardiac troponin I after coronary artery bypass surgery
Thielmann, M.; Massoudy, P.; Schmermund, A. et al. - Efficiency comparisons of rank and permutation tests by Phillip I. Good Statistics in Medicine 2004; 23:857
Neuhäuser, Markus - Endovascular stent-graft placement in aortic dissection : a meta-analysis
Eggebrecht, H.; Nienhaber, C. A.; Neuhäuser, Markus et al. - Exact tests based on the Baumgartner-Weiss-Schindler statistic : a survey
Neuhäuser, Markus - Normalization for Affymetrix GeneChips
Neuhäuser, Markus; Boes, T. - One-Sided Nonparametric Tests for Ordinal Data
Neuhäuser, Markus - Prognostic Value of Preoperative Cardiac Troponin I in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery
Thielmann, Matthias; Massoudy, Parwis; Neuhäuser, Markus et al. - Risk stratification with cardiac troponin I in patients undergoing elective coronary artery bypass surgery
Thielmann, Matthias; Massoudy, Parwis; Neuhäuser, Markus et al. - Two-part permutation tests for DNA methylation and microarray data
Neuhäuser, Markus; Boes, Tanja; Jöckel, K.-H. - Comparing Parasite Numbers Between Samples of Hosts
Neuhäuser, Markus; Poulin, Robert - Einige neue Methoden aus der Biometrie
Neuhäuser, Markus - Maximum Test versus Adaptive Tests for the Two-Sample Location Problem
Neuhäuser, Markus; Büning, Herbert; Hothorn, Ludwig - Testing whether any of the significant tests within a table are indeed significant
Neuhäuser, Markus - Tests for a biased sex ratio when the data are clustered
Neuhäuser, Markus - The Baumgartner-Weiss-Schindler test for the detection of differentially expressed genes in replicated microarray experiments
Neuhäuser, Markus; Senske, Roswitha - The choice of α for one-sided tests
Neuhäuser, Markus - The Fisher-Pitman Permutation Test When Testing for Differences in Mean and Variance
Neuhäuser, Markus; Manly, Bryan F. J. - Wilcoxon Test after Levene's Transformation Can Have an Inflated Type I Error Rate
Neuhäuser, Markus - A Comparison of Procedures for Adaptive Choice of Location Tests in Flexible Two-Stage Designs
Friede, Tim; Kieser, Meinhard; Neuhäuser, Markus et al. - A note on the exact test based on the Baumgartner–Weiß–Schindler statistic in the presence of ties
Neuhäuser, Markus - A Trend Test for the Analysis of Multiple Paternity
Neuhäuser, Markus; Leisler, Bernd; Hothorn, Ludwig A. - Book review of HARDY, I. C. W. (editor). Sex Ratios: Concepts and Research Methods. Cambridge University Press, Cambridge, 2002. xiii + 424 pp. £32.95/$48.00. ISBN 0-521-66578-7.
Neuhäuser, Markus - Further evidence for Emlen's hypothesis from two parrot species
Neuhäuser, Markus - Tests for Genetic Differentiation
Neuhäuser, Markus - Exact Tests for the Analysis of Case-Control Studies of Genetic Markers
Neuhäuser, Markus - Nonparametric identification of the minimum effective dose
Neuhäuser, Markus - The authors replied as follows : The Baumgartner–Weiß–Schindler test in the presence of ties
Neuhäuser, Markus - The New Phosphodiesterase 4 Inhibitor Roflumilast Is Efficacious in Exercise-Induced Asthma and Leads to Suppression of LPS-Stimulated TNF-α Ex Vivo
Timmer, Wolfgang; Leclerc, Violette; Birraux, Guillaume et al. - Two-sample tests when variances are unequal
Neuhäuser, Markus - An Adaptive Location-Scale Test
Neuhäuser, Markus - Nonparametric all-pairs multiple comparisons
Neuhäuser, Markus; Bretz, F. - One-Sided two-sample and trend tests based on a modified baumgartner-weiss-schindler statistic
Neuhäuser, Markus - The distribution of extra-pair young within and among broods : a technique to calculate deviations from randomness
Neuhäuser, Markus; Forstmeier, Wolfgang; Bretz, Frank - The phosphodiesterase 4 inhibitor roflumilast is effective in the treatment of allergic rhinitis
Schmidt, Bernhard M.W.; Kusma, Matthias; Feuring, Martin et al. - An exact two-sample test based on the baumgartner-weiss-schindler statistic and a modification of lepage's test
Neuhäuser, Markus - Equivalence concepts in clinical trials
Neuhäuser, Markus; Steinijans, V. W.; Bretz, F. - Parametric location-scale and scale trend tests based on Levene's transformation
Neuhäuser, Markus; Hothorn, Ludwig A - Robust trend tests with application to toxicology
Neuhäuser, Markus; Seidel, Dirk; Hothorn, Ludwig A. et al. - An exact Cochran–Armitage test for trend when dose–response shapes are a priori unknown
Neuhäuser, Markus; Hothorn, Ludwig A. - The evaluation of multiple clini¬cal endpoints, with application to asthma
Neuhäuser, Markus; Steinijans, V. W.; Bretz, F. - An Analogue of Jonckheere's Trend Test for Parametric and Dichotomous Data
Neuhäuser, Markus; Hothorn, L. A. - Asthma management : the challenge of equivalence
Neuhäuser, Markus; Steinijans, V. W.; Hummel, T. et al. - Nonparametric Tests for Trend : Jonckheere's Test, a Modification and a Maximum Test
Neuhäuser, Markus; Hothorn, L. A.; Liu, P.-Y. - The asymptotic relative efficiency of contrast tests
Neuhäuser, Markus - Adaptive tests for trend
Neuhäuser, M.; Hothorn, L. A. - Analysis of Randomized Dose-Finding-Studies : Closure Test Modifications Based on Multiple Contrast Tests
Hothorn, L. A.; Neuhäuser, M.; Koch, H.-F. - Improved Odds Ratio Estimation by Post Hoc Stratification of Case-control Data
Neuhäuser, Markus; Becher, Heiko - The Control of the Consumer Risk in the Ames Assay
Neuhäuser, Markus; Hothorn, L. A. - Trend Tests for Dichotomous Endpoints with Application to Carcinogenicity Studies
Neuhäuser, Markus; Hothorn, Ludwig A.